CCS is a screening procedure that can be combined with IVF to identify which embryos have the normal number of chromosomes and are the most likely to result in a successful pregnancy and a healthy baby.
Studies have shown that IVF with CCS can achieve:
- Pregnancy rates as high as 70%
- Miscarriage rate as low as 5-10%
- Minimal risk of chromosomal abnormalities such as Down’s syndrome (diagnostic accuracy of CCS is about 99%)
What is the process?
With CCS, eggs are fertilized in the laboratory and the embryo(s) are grown for 5-6 days, at which point a few cells are taken from the outer layer of the embryo(s). This cell layer is called the trophectoderm and it will form the placenta, thus leaving the cells that are destined to become the fetus untouched. The embryos are then frozen and the biopsied cells are sent to a specialized laboratory for testing. The results usually return in 10-14 days. The chromosomally normal embryo can be transferred in the next menstrual cycle.
Who can benefit from CCS?
Any woman going through IVF may consider CCS, but it can be particularly helpful if:
- You are older than 35
- You have experienced miscarriage
- You have a previously unsuccessful IVF
Is there a downside to CCS?
The biggest potential disappointment with CCS is the risk that none of the embryos will be chromosomally normal. The risk for abnormal embryos increases with a woman’s age. For example, for women under 35 the chance of a chromosomally normal embryo is about 55%. For women over age 42, however, that plummets to about 15%.
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